A Decade of Antifungal Leads from Natural Products: 2010–2019

In this review, we discuss novel natural products discovered within the last decade that are reported to have antifungal activity against pathogenic species. Nearly a hundred natural products were identified that originate from bacteria, algae, fungi, sponges, and plants. Fungi were the most prolifi...

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Autores principales: Aldholmi, Mohammed, Marchand, Pascal, Ourliac-Garnier, Isabelle, Le Pape, Patrice, Ganesan, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958371/
https://www.ncbi.nlm.nih.gov/pubmed/31842280
http://dx.doi.org/10.3390/ph12040182
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author Aldholmi, Mohammed
Marchand, Pascal
Ourliac-Garnier, Isabelle
Le Pape, Patrice
Ganesan, A.
author_facet Aldholmi, Mohammed
Marchand, Pascal
Ourliac-Garnier, Isabelle
Le Pape, Patrice
Ganesan, A.
author_sort Aldholmi, Mohammed
collection PubMed
description In this review, we discuss novel natural products discovered within the last decade that are reported to have antifungal activity against pathogenic species. Nearly a hundred natural products were identified that originate from bacteria, algae, fungi, sponges, and plants. Fungi were the most prolific source of antifungal compounds discovered during the period of review. The structural diversity of these antifungal leads encompasses all the major classes of natural products including polyketides, shikimate metabolites, terpenoids, alkaloids, and peptides.
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spelling pubmed-69583712020-01-23 A Decade of Antifungal Leads from Natural Products: 2010–2019 Aldholmi, Mohammed Marchand, Pascal Ourliac-Garnier, Isabelle Le Pape, Patrice Ganesan, A. Pharmaceuticals (Basel) Review In this review, we discuss novel natural products discovered within the last decade that are reported to have antifungal activity against pathogenic species. Nearly a hundred natural products were identified that originate from bacteria, algae, fungi, sponges, and plants. Fungi were the most prolific source of antifungal compounds discovered during the period of review. The structural diversity of these antifungal leads encompasses all the major classes of natural products including polyketides, shikimate metabolites, terpenoids, alkaloids, and peptides. MDPI 2019-12-12 /pmc/articles/PMC6958371/ /pubmed/31842280 http://dx.doi.org/10.3390/ph12040182 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Aldholmi, Mohammed
Marchand, Pascal
Ourliac-Garnier, Isabelle
Le Pape, Patrice
Ganesan, A.
A Decade of Antifungal Leads from Natural Products: 2010–2019
title A Decade of Antifungal Leads from Natural Products: 2010–2019
title_full A Decade of Antifungal Leads from Natural Products: 2010–2019
title_fullStr A Decade of Antifungal Leads from Natural Products: 2010–2019
title_full_unstemmed A Decade of Antifungal Leads from Natural Products: 2010–2019
title_short A Decade of Antifungal Leads from Natural Products: 2010–2019
title_sort decade of antifungal leads from natural products: 2010–2019
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958371/
https://www.ncbi.nlm.nih.gov/pubmed/31842280
http://dx.doi.org/10.3390/ph12040182
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