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A Long-Term Study of the Biological Properties of ASF Virus Isolates Originating from Various Regions of the Russian Federation in 2013–2018

Biological properties of the African swine fever (ASF) virus isolates originating from various regions of the Russian Federation (2013–2018) were studied in a series of experimental infections. Comparative analysis allowed us to establish the differences in the key characteristics of the infection,...

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Autores principales: Pershin, Andrei, Shevchenko, Ivan, Igolkin, Alexey, Zhukov, Ivan, Mazloum, Ali, Aronova, Elena, Vlasova, Natalia, Shevtsov, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958400/
https://www.ncbi.nlm.nih.gov/pubmed/31817809
http://dx.doi.org/10.3390/vetsci6040099
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author Pershin, Andrei
Shevchenko, Ivan
Igolkin, Alexey
Zhukov, Ivan
Mazloum, Ali
Aronova, Elena
Vlasova, Natalia
Shevtsov, Alexander
author_facet Pershin, Andrei
Shevchenko, Ivan
Igolkin, Alexey
Zhukov, Ivan
Mazloum, Ali
Aronova, Elena
Vlasova, Natalia
Shevtsov, Alexander
author_sort Pershin, Andrei
collection PubMed
description Biological properties of the African swine fever (ASF) virus isolates originating from various regions of the Russian Federation (2013–2018) were studied in a series of experimental infections. Comparative analysis allowed us to establish the differences in the key characteristics of the infection, such us the duration of the incubation periods, disease, and the onset of death. The incubation period averaged 4.1 days, varying from 1 to 13 days. An average duration of the disease was 6.3 days and varied from 0 to 18 days. Overall case fatality was 94.5%, and antibodies were detected only in 19.3% of the animals. The biological properties of isolates Odintsovo 02/14 and Lipetsk 12/16 were significantly different from others. For this two, the presence of antibodies to the virus was detected in 71.4% and 75% of animals respectively and mortality levels were of 87.5% and 50%.
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spelling pubmed-69584002020-01-23 A Long-Term Study of the Biological Properties of ASF Virus Isolates Originating from Various Regions of the Russian Federation in 2013–2018 Pershin, Andrei Shevchenko, Ivan Igolkin, Alexey Zhukov, Ivan Mazloum, Ali Aronova, Elena Vlasova, Natalia Shevtsov, Alexander Vet Sci Article Biological properties of the African swine fever (ASF) virus isolates originating from various regions of the Russian Federation (2013–2018) were studied in a series of experimental infections. Comparative analysis allowed us to establish the differences in the key characteristics of the infection, such us the duration of the incubation periods, disease, and the onset of death. The incubation period averaged 4.1 days, varying from 1 to 13 days. An average duration of the disease was 6.3 days and varied from 0 to 18 days. Overall case fatality was 94.5%, and antibodies were detected only in 19.3% of the animals. The biological properties of isolates Odintsovo 02/14 and Lipetsk 12/16 were significantly different from others. For this two, the presence of antibodies to the virus was detected in 71.4% and 75% of animals respectively and mortality levels were of 87.5% and 50%. MDPI 2019-12-06 /pmc/articles/PMC6958400/ /pubmed/31817809 http://dx.doi.org/10.3390/vetsci6040099 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pershin, Andrei
Shevchenko, Ivan
Igolkin, Alexey
Zhukov, Ivan
Mazloum, Ali
Aronova, Elena
Vlasova, Natalia
Shevtsov, Alexander
A Long-Term Study of the Biological Properties of ASF Virus Isolates Originating from Various Regions of the Russian Federation in 2013–2018
title A Long-Term Study of the Biological Properties of ASF Virus Isolates Originating from Various Regions of the Russian Federation in 2013–2018
title_full A Long-Term Study of the Biological Properties of ASF Virus Isolates Originating from Various Regions of the Russian Federation in 2013–2018
title_fullStr A Long-Term Study of the Biological Properties of ASF Virus Isolates Originating from Various Regions of the Russian Federation in 2013–2018
title_full_unstemmed A Long-Term Study of the Biological Properties of ASF Virus Isolates Originating from Various Regions of the Russian Federation in 2013–2018
title_short A Long-Term Study of the Biological Properties of ASF Virus Isolates Originating from Various Regions of the Russian Federation in 2013–2018
title_sort long-term study of the biological properties of asf virus isolates originating from various regions of the russian federation in 2013–2018
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958400/
https://www.ncbi.nlm.nih.gov/pubmed/31817809
http://dx.doi.org/10.3390/vetsci6040099
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