Cargando…
Amino-3,5-Dicyanopyridines Targeting the Adenosine Receptors. Ranging from Pan Ligands to Combined A1/A2B Partial Agonists
The amino-3,5-dicyanopyridine derivatives belong to an intriguing series of adenosine receptor (AR) ligands that has been developed by both academic researchers and industry. Indeed, the studies carried out to date underline the versatility of the dicyanopyridine scaffold to obtain AR ligands with n...
Autores principales: | Catarzi, Daniela, Varano, Flavia, Varani, Katia, Vincenzi, Fabrizio, Pasquini, Silvia, Dal Ben, Diego, Volpini, Rosaria, Colotta, Vittoria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958422/ https://www.ncbi.nlm.nih.gov/pubmed/31652622 http://dx.doi.org/10.3390/ph12040159 |
Ejemplares similares
-
4-Heteroaryl Substituted Amino-3,5-Dicyanopyridines as New Adenosine Receptor Ligands: Novel Insights on Structure-Activity Relationships and Perspectives
por: Catarzi, Daniela, et al.
Publicado: (2022) -
Piperazine- and Piperidine-Containing Thiazolo[5,4-d]pyrimidine Derivatives as New Potent and Selective Adenosine A(2A) Receptor Inverse Agonists
por: Varano, Flavia, et al.
Publicado: (2020) -
Special Issue “Adenosine Receptors as Attractive Targets in Human Diseases”
por: Catarzi, Daniela, et al.
Publicado: (2021) -
Inhibition of A(2A) Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455
por: Gessi, Stefania, et al.
Publicado: (2017) -
The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A(1) and A(2A) receptor affinity and selectivity profiles
por: Squarcialupi, Lucia, et al.
Publicado: (2017)