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Assembly and Function of Gonad-Specific Non-Membranous Organelles in Drosophila piRNA Biogenesis
PIWI-interacting RNAs (piRNAs) are small non-coding RNAs that repress transposons in animal germlines. This protects the genome from the invasive DNA elements. piRNA pathway failures lead to DNA damage, gonadal development defects, and infertility. Thus, the piRNA pathway is indispensable for the co...
Autores principales: | Hirakata, Shigeki, Siomi, Mikiko C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958439/ https://www.ncbi.nlm.nih.gov/pubmed/31698692 http://dx.doi.org/10.3390/ncrna5040052 |
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