Large-Scale Chemical-Genetic Strategy Enables the Design of Antimicrobial Combination Chemotherapy in Mycobacteria

[Image: see text] The efficacies of all antibiotics against tuberculosis are eventually eroded by resistance. New strategies to discover drugs or drug combinations with higher barriers to resistance are needed. Previously, we reported the application of a large-scale chemical-genetic interaction scr...

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Detalles Bibliográficos
Autores principales: Johnson, Eachan O., Office, Emma, Kawate, Tomohiko, Orzechowski, Marek, Hung, Deborah T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958538/
https://www.ncbi.nlm.nih.gov/pubmed/31721551
http://dx.doi.org/10.1021/acsinfecdis.9b00373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958538/
https://www.ncbi.nlm.nih.gov/pubmed/31721551
http://dx.doi.org/10.1021/acsinfecdis.9b00373

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