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SCHISTOSOMAL MYELORADICULOPATHY IN A NON-ENDEMIC AREA

OBJECTIVE: To report a schistosomal myeloradiculopathy case in a non-endemic area. CASE DESCRIPTION: A previously healthy 11-year-old boy, stricken by an acute loss of strength on his lower limbs, followed by a loss of strength on his upper limbs and upper body, associated with altered sensitivity o...

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Autores principales: de Oliveira, Lívia Souza, Kuzma, Gabriela de Sio Puetter, Costa, Luisa Carolina Vinhal, João, Paulo Ramos David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade de Pediatria de São Paulo 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958542/
https://www.ncbi.nlm.nih.gov/pubmed/31939512
http://dx.doi.org/10.1590/1984-0462/2020/38/2018232
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author de Oliveira, Lívia Souza
Kuzma, Gabriela de Sio Puetter
Costa, Luisa Carolina Vinhal
João, Paulo Ramos David
author_facet de Oliveira, Lívia Souza
Kuzma, Gabriela de Sio Puetter
Costa, Luisa Carolina Vinhal
João, Paulo Ramos David
author_sort de Oliveira, Lívia Souza
collection PubMed
description OBJECTIVE: To report a schistosomal myeloradiculopathy case in a non-endemic area. CASE DESCRIPTION: A previously healthy 11-year-old boy, stricken by an acute loss of strength on his lower limbs, followed by a loss of strength on his upper limbs and upper body, associated with altered sensitivity of the vesical globe formation. The patient’s cerebrospinal fluid analysis showed eosinophilic meningitis, in addition to peripheral eosinophilia. The investigation resulted in a positive serology for Schistosoma mansoni. The treatment included steroids and praziquantel 60mg/kg, with a new dose after a month, as well as physical therapy for rehabilitation. The patient evolved with clinical improvement in the neurological exam, with a medullary section initially at C6, but now at T6. The patient is kept at prednisolone use (30mg/day) and longterm urinary catheter dependence. COMMENTS: The schistosomiasis is endemic in many regions of Brazil; however, it has low incidence in the south of the country. Among its main manifestations, the schistosomal myeloradiculopathy is the most severe ectopic form of the disease, and should be suspected in patients with low back pain, strength and/or sensibility disorder of the lower limbs or urinary tract’s disturbance. Early diagnosis and treatment should be done in order to reduce severe neurological sequelae. Treatment includes schistosomiasis drugs, corticosteroids and/or surgery.
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spelling pubmed-69585422020-01-23 SCHISTOSOMAL MYELORADICULOPATHY IN A NON-ENDEMIC AREA de Oliveira, Lívia Souza Kuzma, Gabriela de Sio Puetter Costa, Luisa Carolina Vinhal João, Paulo Ramos David Rev Paul Pediatr Case Report OBJECTIVE: To report a schistosomal myeloradiculopathy case in a non-endemic area. CASE DESCRIPTION: A previously healthy 11-year-old boy, stricken by an acute loss of strength on his lower limbs, followed by a loss of strength on his upper limbs and upper body, associated with altered sensitivity of the vesical globe formation. The patient’s cerebrospinal fluid analysis showed eosinophilic meningitis, in addition to peripheral eosinophilia. The investigation resulted in a positive serology for Schistosoma mansoni. The treatment included steroids and praziquantel 60mg/kg, with a new dose after a month, as well as physical therapy for rehabilitation. The patient evolved with clinical improvement in the neurological exam, with a medullary section initially at C6, but now at T6. The patient is kept at prednisolone use (30mg/day) and longterm urinary catheter dependence. COMMENTS: The schistosomiasis is endemic in many regions of Brazil; however, it has low incidence in the south of the country. Among its main manifestations, the schistosomal myeloradiculopathy is the most severe ectopic form of the disease, and should be suspected in patients with low back pain, strength and/or sensibility disorder of the lower limbs or urinary tract’s disturbance. Early diagnosis and treatment should be done in order to reduce severe neurological sequelae. Treatment includes schistosomiasis drugs, corticosteroids and/or surgery. Sociedade de Pediatria de São Paulo 2020-01-13 /pmc/articles/PMC6958542/ /pubmed/31939512 http://dx.doi.org/10.1590/1984-0462/2020/38/2018232 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Case Report
de Oliveira, Lívia Souza
Kuzma, Gabriela de Sio Puetter
Costa, Luisa Carolina Vinhal
João, Paulo Ramos David
SCHISTOSOMAL MYELORADICULOPATHY IN A NON-ENDEMIC AREA
title SCHISTOSOMAL MYELORADICULOPATHY IN A NON-ENDEMIC AREA
title_full SCHISTOSOMAL MYELORADICULOPATHY IN A NON-ENDEMIC AREA
title_fullStr SCHISTOSOMAL MYELORADICULOPATHY IN A NON-ENDEMIC AREA
title_full_unstemmed SCHISTOSOMAL MYELORADICULOPATHY IN A NON-ENDEMIC AREA
title_short SCHISTOSOMAL MYELORADICULOPATHY IN A NON-ENDEMIC AREA
title_sort schistosomal myeloradiculopathy in a non-endemic area
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958542/
https://www.ncbi.nlm.nih.gov/pubmed/31939512
http://dx.doi.org/10.1590/1984-0462/2020/38/2018232
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