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The Nucleolin Antagonist N6L Inhibits LINE1 Retrotransposon Activity in Non-Small Cell Lung Carcinoma Cells

Lung cancer is the most common cause of cancer death in the United States. The genome of non-small cell lung cancer (NSCLC), the most frequent lung cancer type, is strongly affected by Long Interspersed Nuclear Element (LINE1) insertions. Active LINE1s are repetitive DNA sequences that can amplify t...

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Detalles Bibliográficos
Autores principales: Ramos, Kenneth S., Moore, Sara, Runge, Isabel, Tavera-Garcia, Marco A., Cascone, Ilaria, Courty, Jose, Reyes-Reyes, Elsa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959038/
https://www.ncbi.nlm.nih.gov/pubmed/31942196
http://dx.doi.org/10.7150/jca.37776