Increased Tim-3 expression on TILs during treatment with the Anchored GM-CSF vaccine and anti-PD-1 antibodies is inversely correlated with response in prostate cancer

Programmed death receptor-1 (PD-1) and T cell immunoglobulin and mucin domain-containing protein-3 (Tim-3) play important roles in tumor immune evasion. PD-1 blockade could produce an effective antitumor effect in many solid tumors except prostate cancer (PCa) because of rare programmed death ligand...

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Detalles Bibliográficos
Autores principales: Zhang, Xinji, Chen, Haixiong, Li, Guanfeng, Zhou, Xiangyun, Shi, Yuqiang, Zou, Feng, Chen, Yuanxiang, Gao, Jimin, Yang, Shaomin, Wu, Shihao, Long, Zhaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959042/
https://www.ncbi.nlm.nih.gov/pubmed/31942188
http://dx.doi.org/10.7150/jca.29705

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