Role of Imaging in Diagnosis of a Rare Hepatosplenic Gamma Delta T-Cell Lymphoma during Pregnancy: A Case Report and Review of Literature

Hepatosplenic γδ T-cell lymphoma (HSTCL) is a very rare peripheral T-cell lymphoma characterized by extranodal infiltration of mature malignant post-thymic T-lymphocytes into sinusoids of the liver and spleen without lymphadenopathy and significant cytopenias. It is an aggressive form of lymphoma, r...

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Autores principales: Youssef, Reda R.H., Elmahdy, Amr, Kohla, Samah, Ibrahim, Feryal, Sabry, Ahmed Saied, Alobaidly, Amal, Saloum, Nehal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959114/
https://www.ncbi.nlm.nih.gov/pubmed/31966031
http://dx.doi.org/10.1159/000504568
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author Youssef, Reda R.H.
Elmahdy, Amr
Kohla, Samah
Ibrahim, Feryal
Sabry, Ahmed Saied
Alobaidly, Amal
Saloum, Nehal
author_facet Youssef, Reda R.H.
Elmahdy, Amr
Kohla, Samah
Ibrahim, Feryal
Sabry, Ahmed Saied
Alobaidly, Amal
Saloum, Nehal
author_sort Youssef, Reda R.H.
collection PubMed
description Hepatosplenic γδ T-cell lymphoma (HSTCL) is a very rare peripheral T-cell lymphoma characterized by extranodal infiltration of mature malignant post-thymic T-lymphocytes into sinusoids of the liver and spleen without lymphadenopathy and significant cytopenias. It is an aggressive form of lymphoma, resistant to the conventional chemotherapy. We report a case of HSTCL in pregnancy. Because this condition is an extremely aggressive and rare entity, data from these cases can help confirm the most suitable treatment regimen and timing of initiation. The role of ultrasound and magnetic resonance imaging in the diagnosis has been discussed. HSTCL is a rare entity of T-cell lymphoma, uncommon in female patients and very rarely reported during pregnancy.
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spelling pubmed-69591142020-01-21 Role of Imaging in Diagnosis of a Rare Hepatosplenic Gamma Delta T-Cell Lymphoma during Pregnancy: A Case Report and Review of Literature Youssef, Reda R.H. Elmahdy, Amr Kohla, Samah Ibrahim, Feryal Sabry, Ahmed Saied Alobaidly, Amal Saloum, Nehal Case Rep Oncol Case Report Hepatosplenic γδ T-cell lymphoma (HSTCL) is a very rare peripheral T-cell lymphoma characterized by extranodal infiltration of mature malignant post-thymic T-lymphocytes into sinusoids of the liver and spleen without lymphadenopathy and significant cytopenias. It is an aggressive form of lymphoma, resistant to the conventional chemotherapy. We report a case of HSTCL in pregnancy. Because this condition is an extremely aggressive and rare entity, data from these cases can help confirm the most suitable treatment regimen and timing of initiation. The role of ultrasound and magnetic resonance imaging in the diagnosis has been discussed. HSTCL is a rare entity of T-cell lymphoma, uncommon in female patients and very rarely reported during pregnancy. S. Karger AG 2019-12-20 /pmc/articles/PMC6959114/ /pubmed/31966031 http://dx.doi.org/10.1159/000504568 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Youssef, Reda R.H.
Elmahdy, Amr
Kohla, Samah
Ibrahim, Feryal
Sabry, Ahmed Saied
Alobaidly, Amal
Saloum, Nehal
Role of Imaging in Diagnosis of a Rare Hepatosplenic Gamma Delta T-Cell Lymphoma during Pregnancy: A Case Report and Review of Literature
title Role of Imaging in Diagnosis of a Rare Hepatosplenic Gamma Delta T-Cell Lymphoma during Pregnancy: A Case Report and Review of Literature
title_full Role of Imaging in Diagnosis of a Rare Hepatosplenic Gamma Delta T-Cell Lymphoma during Pregnancy: A Case Report and Review of Literature
title_fullStr Role of Imaging in Diagnosis of a Rare Hepatosplenic Gamma Delta T-Cell Lymphoma during Pregnancy: A Case Report and Review of Literature
title_full_unstemmed Role of Imaging in Diagnosis of a Rare Hepatosplenic Gamma Delta T-Cell Lymphoma during Pregnancy: A Case Report and Review of Literature
title_short Role of Imaging in Diagnosis of a Rare Hepatosplenic Gamma Delta T-Cell Lymphoma during Pregnancy: A Case Report and Review of Literature
title_sort role of imaging in diagnosis of a rare hepatosplenic gamma delta t-cell lymphoma during pregnancy: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959114/
https://www.ncbi.nlm.nih.gov/pubmed/31966031
http://dx.doi.org/10.1159/000504568
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