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Association of glomerular DNA damage and DNA methylation with one-year eGFR decline in IgA nephropathy

Accumulation of DNA double-strand breaks (DSBs) is linked to aging and age-related diseases. We recently reported the possible association of DNA DSBs with altered DNA methylation in murine models of kidney disease. However, DSBs and DNA methylation in human kidneys was not adequately investigated....

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Detalles Bibliográficos
Autores principales:	Hayashi, Kaori, Hishikawa, Akihito, Hashiguchi, Akinori, Azegami, Tatsuhiko, Yoshimoto, Norifumi, Nakamichi, Ran, Tokuyama, Hirobumi, Itoh, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959244/ https://www.ncbi.nlm.nih.gov/pubmed/31937846 http://dx.doi.org/10.1038/s41598-019-57140-0

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