Cloning and analysis of PRNP gene of Vulpes corsac in Qinghai plateau, China

PRNP gene encodes PrP protein, which is conservative among different species and associates with the susceptibility of prion disease. In this report, we cloned and sequenced the full-length PRNP gene of Vulpes corsac in Qinghai plateau, China. The amino acid sequence of Vulpes corsac PrP showed 100%...

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Detalles Bibliográficos
Autores principales: Yang, Xue-Hua, Xiao, Kang, Wu, Yuezhang, Gao, Liping, Chen, Dongdong, Dong, Xiao-Ping, Shi, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959281/
https://www.ncbi.nlm.nih.gov/pubmed/31880206
http://dx.doi.org/10.1080/19336896.2019.1704496
Descripción
Sumario:PRNP gene encodes PrP protein, which is conservative among different species and associates with the susceptibility of prion disease. In this report, we cloned and sequenced the full-length PRNP gene of Vulpes corsac in Qinghai plateau, China. The amino acid sequence of Vulpes corsac PrP showed 100% homology with those of the other three species of foxes. The taxa relationship of Vulpes corsac PrP with other species of animals, including human, canine, bovine, cervus, capra, ovis, camelus, felis, Mustela, mouse and hamster were also analysed.

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