Cloning and analysis of PRNP gene of Vulpes corsac in Qinghai plateau, China

PRNP gene encodes PrP protein, which is conservative among different species and associates with the susceptibility of prion disease. In this report, we cloned and sequenced the full-length PRNP gene of Vulpes corsac in Qinghai plateau, China. The amino acid sequence of Vulpes corsac PrP showed 100%...

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Autores principales: Yang, Xue-Hua, Xiao, Kang, Wu, Yuezhang, Gao, Liping, Chen, Dongdong, Dong, Xiao-Ping, Shi, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959281/
https://www.ncbi.nlm.nih.gov/pubmed/31880206
http://dx.doi.org/10.1080/19336896.2019.1704496
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author Yang, Xue-Hua
Xiao, Kang
Wu, Yuezhang
Gao, Liping
Chen, Dongdong
Dong, Xiao-Ping
Shi, Qi
author_facet Yang, Xue-Hua
Xiao, Kang
Wu, Yuezhang
Gao, Liping
Chen, Dongdong
Dong, Xiao-Ping
Shi, Qi
author_sort Yang, Xue-Hua
collection PubMed
description PRNP gene encodes PrP protein, which is conservative among different species and associates with the susceptibility of prion disease. In this report, we cloned and sequenced the full-length PRNP gene of Vulpes corsac in Qinghai plateau, China. The amino acid sequence of Vulpes corsac PrP showed 100% homology with those of the other three species of foxes. The taxa relationship of Vulpes corsac PrP with other species of animals, including human, canine, bovine, cervus, capra, ovis, camelus, felis, Mustela, mouse and hamster were also analysed.
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spelling pubmed-69592812020-01-24 Cloning and analysis of PRNP gene of Vulpes corsac in Qinghai plateau, China Yang, Xue-Hua Xiao, Kang Wu, Yuezhang Gao, Liping Chen, Dongdong Dong, Xiao-Ping Shi, Qi Prion Short Communication PRNP gene encodes PrP protein, which is conservative among different species and associates with the susceptibility of prion disease. In this report, we cloned and sequenced the full-length PRNP gene of Vulpes corsac in Qinghai plateau, China. The amino acid sequence of Vulpes corsac PrP showed 100% homology with those of the other three species of foxes. The taxa relationship of Vulpes corsac PrP with other species of animals, including human, canine, bovine, cervus, capra, ovis, camelus, felis, Mustela, mouse and hamster were also analysed. Taylor & Francis 2019-12-27 /pmc/articles/PMC6959281/ /pubmed/31880206 http://dx.doi.org/10.1080/19336896.2019.1704496 Text en © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Yang, Xue-Hua
Xiao, Kang
Wu, Yuezhang
Gao, Liping
Chen, Dongdong
Dong, Xiao-Ping
Shi, Qi
Cloning and analysis of PRNP gene of Vulpes corsac in Qinghai plateau, China
title Cloning and analysis of PRNP gene of Vulpes corsac in Qinghai plateau, China
title_full Cloning and analysis of PRNP gene of Vulpes corsac in Qinghai plateau, China
title_fullStr Cloning and analysis of PRNP gene of Vulpes corsac in Qinghai plateau, China
title_full_unstemmed Cloning and analysis of PRNP gene of Vulpes corsac in Qinghai plateau, China
title_short Cloning and analysis of PRNP gene of Vulpes corsac in Qinghai plateau, China
title_sort cloning and analysis of prnp gene of vulpes corsac in qinghai plateau, china
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959281/
https://www.ncbi.nlm.nih.gov/pubmed/31880206
http://dx.doi.org/10.1080/19336896.2019.1704496
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