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Multifaceted role of SMCR8 as autophagy regulator
Through autophagy intracellular material is engulfed by double membrane vesicles and delivered to lysosomes for degradation. This process requires Rab GTPases, Rab GAPs and Rab GEFs for proper membrane trafficking, since they control vesicle budding, targeting and fusion. Deregulation of autophagy c...
Autores principales: | Jung, Jennifer, Behrends, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959302/ https://www.ncbi.nlm.nih.gov/pubmed/28696821 http://dx.doi.org/10.1080/21541248.2017.1346553 |
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