Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis

Differentiation and homeostasis of Foxp3(+) regulatory T (Treg) cells are strictly controlled by T-cell receptor (TCR) signals; however, molecular mechanisms that govern these processes are incompletely understood. Here we show that Bach2 is an important regulator of Treg cell differentiation and ho...

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Detalles Bibliográficos
Autores principales: Sidwell, Tom, Liao, Yang, Garnham, Alexandra L., Vasanthakumar, Ajithkumar, Gloury, Renee, Blume, Jonas, Teh, Peggy P., Chisanga, David, Thelemann, Christoph, de Labastida Rivera, Fabian, Engwerda, Christian R., Corcoran, Lynn, Kometani, Kohei, Kurosaki, Tomohiro, Smyth, Gordon K., Shi, Wei, Kallies, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959360/
https://www.ncbi.nlm.nih.gov/pubmed/31937752
http://dx.doi.org/10.1038/s41467-019-14112-2

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