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The ETFL formulation allows multi-omics integration in thermodynamics-compliant metabolism and expression models
Systems biology has long been interested in models capturing both metabolism and expression in a cell. We propose here an implementation of the metabolism and expression model formalism (ME-models), which we call ETFL, for Expression and Thermodynamics Flux models. ETFL is a hierarchical model formu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959363/ https://www.ncbi.nlm.nih.gov/pubmed/31937763 http://dx.doi.org/10.1038/s41467-019-13818-7 |