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High-yield Production of Amyloid-β Peptide Enabled by a Customized Spider Silk Domain

During storage in the silk gland, the N-terminal domain (NT) of spider silk proteins (spidroins) keeps the aggregation-prone repetitive region in solution at extreme concentrations. We observe that NTs from different spidroins have co-evolved with their respective repeat region, and now use an NT th...

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Detalles Bibliográficos
Autores principales:	Abelein, Axel, Chen, Gefei, Kitoka, Kristīne, Aleksis, Rihards, Oleskovs, Filips, Sarr, Médoune, Landreh, Michael, Pahnke, Jens, Nordling, Kerstin, Kronqvist, Nina, Jaudzems, Kristaps, Rising, Anna, Johansson, Jan, Biverstål, Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959368/ https://www.ncbi.nlm.nih.gov/pubmed/31937841 http://dx.doi.org/10.1038/s41598-019-57143-x

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