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Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome

Immune checkpoint blockade (ICPB) is a powerfully effective cancer therapy in some patients. Tumor neo-antigens are likely main targets for attack but it is not clear which and how many tumor mutations in individual cancers are actually antigenic, with or without ICPB therapy and their role as neo-a...

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Detalles Bibliográficos
Autores principales:	Ma, Shaokang, Chee, Jonathan, Fear, Vanessa S., Forbes, Catherine A., Boon, Louis, Dick, Ian M., Robinson, Bruce W. S., Creaney, Jenette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959436/ https://www.ncbi.nlm.nih.gov/pubmed/32002299 http://dx.doi.org/10.1080/2162402X.2019.1684714

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