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Establishing a model system for evaluating CAR T cell therapy using dogs with spontaneous diffuse large B cell lymphoma

Multiple rodent and primate preclinical studies have advanced CAR T cells into the clinic. However, no single model accurately reflects the challenges of effective CAR T therapy in human cancer patients. To evaluate the effectiveness of next-generation CAR T cells that aim to overcome barriers to du...

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Detalles Bibliográficos
Autores principales:	Panjwani, M. Kazim, Atherton, Matthew J., MaloneyHuss, Martha A., Haran, Kumudhini P., Xiong, Ailian, Gupta, Minnal, Kulikovsaya, Irina, Lacey, Simon F., Mason, Nicola J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959441/ https://www.ncbi.nlm.nih.gov/pubmed/32002286 http://dx.doi.org/10.1080/2162402X.2019.1676615

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