ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity

Alpha thalassemia/mental retardation syndrome X-linked chromatin remodeler (ATRX), a DAXX (death domain-associated protein) interacting protein, is often lost in cells using the alternative lengthening of telomeres (ALT) pathway, but it is not known how ATRX loss leads to ALT. We report that ATRX de...

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Detalles Bibliográficos
Autores principales: Lovejoy, Courtney A., Takai, Kaori, Huh, Michael S., Picketts, David J., de Lange, Titia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959610/
https://www.ncbi.nlm.nih.gov/pubmed/31895940
http://dx.doi.org/10.1371/journal.pbio.3000594

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