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Aberrantly High Levels of Somatic LINE-1 Expression and Retrotransposition in Human Neurological Disorders
Retrotransposable elements (RTEs) have actively multiplied over the past 80 million years of primate evolution, and as a consequence, such elements collectively occupy ∼ 40% of the human genome. As RTE activity can have detrimental effects on the human genome and transcriptome, silencing mechanisms...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960195/ https://www.ncbi.nlm.nih.gov/pubmed/31969897 http://dx.doi.org/10.3389/fgene.2019.01244 |