Cargando…

KLHL1 Controls Ca(V)3.2 Expression in DRG Neurons and Mechanical Sensitivity to Pain

Dorsal root ganglion (DRG) neurons process pain signaling through specialized nociceptors located in their peripheral endings. It has long been established low voltage-activated (LVA) Ca(V)3.2 calcium channels control neuronal excitability during sensory perception in these neurons. Silencing Ca(V)3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martínez-Hernández, Elizabeth, Zeglin, Alissa, Almazan, Erik, Perissinotti, Paula, He, Yungui, Koob, Michael, Martin, Jody L., Piedras-Rentería, Erika S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960199/ https://www.ncbi.nlm.nih.gov/pubmed/31969803 http://dx.doi.org/10.3389/fnmol.2019.00315

Ejemplares similares

Genetic Deletion of KLHL1 Leads to Hyperexcitability in Hypothalamic POMC Neurons and Lack of Electrical Responses to Leptin
por: Perissinotti, Paula P., et al.
Publicado: (2021)

Calcium current homeostasis and synaptic deficits in hippocampal neurons from Kelch-like 1 knockout mice
por: Perissinotti, Paula P., et al.
Publicado: (2015)

TRPC1/5-Ca(V)3 Complex Mediates Leptin-Induced Excitability in Hypothalamic Neurons
por: Perissinotti, Paula P., et al.
Publicado: (2021)

Increased expression of Ca(V)3.2 T-type calcium channels in damaged DRG neurons contributes to neuropathic pain in rats with spared nerve injury
por: Kang, Xue-Jing, et al.
Publicado: (2018)

KLHL5 knockdown increases cellular sensitivity to anticancer drugs
por: Schleifer, Robert J., et al.
Publicado: (2018)

Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons
por: Anand, Uma, et al.
Publicado: (2010)

Influence of gap junctions upon Ca(2+) propagation from stimulated keratinocytes to DRG neurons
por: Seto, Chiaki, et al.
Publicado: (2022)

Elimination of the Actin-Binding Domain in Kelch-Like 1 Protein Induces T-Type Calcium Channel Modulation Only in the Presence of Action Potential Waveforms
por: Aromolaran, Kelly A., et al.
Publicado: (2012)

Pretreatment with Zonisamide Mitigates Oxaliplatin-Induced Toxicity in Rat DRG Neurons and DRG Neuron–Schwann Cell Co-Cultures
por: Takaku, Shizuka, et al.
Publicado: (2022)

Daidzein induces neuritogenesis in DRG neuronal cultures
por: Yang, Shih-Hung, et al.
Publicado: (2012)

Clinical Outcome in KLHL24 Cardiomyopathy
por: Vermeer, Mathilde C.S.C., et al.
Publicado: (2023)

Diabetes-Induced Amplification of Nociceptive DRG Neuron Output by Upregulation of Somatic T-Type Ca(2+) Channels
por: Ivasiuk, Arsentii, et al.
Publicado: (2023)

VGLUTs and Glutamate Synthesis—Focus on DRG Neurons and Pain
por: Malet, Mariana, et al.
Publicado: (2015)

Update on the Kelch-like (KLHL) gene family
por: Dhanoa, Bajinder S, et al.
Publicado: (2013)

A TLR–CXCL1 pathway in DRG neurons induces neutrophil accumulation in the DRG and mechanical allodynia in EAE mice
por: Zhang, Jing, et al.
Publicado: (2019)

Teaching About Contraception: Adolescent Attitudes Surrounding Sexual Education
por: Zeglin, Alissa, et al.
Publicado: (2023)

Overexpression of KLHL23 protein from read‐through transcription of PHOSPHO2‐KLHL23 in gastric cancer increases cell proliferation
por: Choi, Eun‐Seok, et al.
Publicado: (2016)

Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from rats
por: Du, Xiaona, et al.
Publicado: (2011)

The Endocannabinoid Analgesic Entourage Effect: Investigations in Cultured DRG Neurons
por: Anand, Uma, et al.
Publicado: (2022)

Crystal Structure of KLHL3 in Complex with Cullin3
por: Ji, Alan X., et al.
Publicado: (2013)

Cardiomyopathy with lethal arrhythmias associated with inactivation of KLHL24
por: Hedberg-Oldfors, Carola, et al.
Publicado: (2019)

A synthetic KLHL20 ligand to validate CUL3(KLHL20) as a potent E3 ligase for targeted protein degradation
por: Farrell, Brian M., et al.
Publicado: (2022)

Inhibition of Hyperpolarization-Activated Cation Current in Medium-Sized DRG Neurons Contributed to the Antiallodynic Effect of Methylcobalamin in the Rat of a Chronic Compression of the DRG
por: Zhang, Ming, et al.
Publicado: (2015)

CFTR mediates noradrenaline-induced ATP efflux from DRG neurons
por: Kanno, Takeshi, et al.
Publicado: (2011)

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone
por: Song, Ok-Ryul, et al.
Publicado: (2017)

Functional Expression of Piezo1 in Dorsal Root Ganglion (DRG) Neurons
por: Roh, Jueun, et al.
Publicado: (2020)

CBD Effects on TRPV1 Signaling Pathways in Cultured DRG Neurons
por: Anand, Uma, et al.
Publicado: (2020)

TSLP in DRG neurons causes the development of neuropathic pain through T cells
por: Ino, Yuka, et al.
Publicado: (2023)

KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination
por: Ramirez-Martinez, Andres, et al.
Publicado: (2017)

Epigenetics of Muscle- and Brain-Specific Expression of KLHL Family Genes
por: Ehrlich, Kenneth C., et al.
Publicado: (2020)

Comparison of the Force Exerted by Hippocampal and DRG Growth Cones
por: Amin, Ladan, et al.
Publicado: (2013)

A Developmental Switch in the Response of DRG Neurons to ETS Transcription Factor Signaling
por: Hippenmeyer, Simon, et al.
Publicado: (2005)

Comparative functional expression of nAChR subtypes in rodent DRG neurons
por: Smith, Nathan J., et al.
Publicado: (2013)

The Role of Rac1 in the Growth Cone Dynamics and Force Generation of DRG Neurons
por: Sayyad, Wasim A., et al.
Publicado: (2016)

Nociceptive DRG neurons express muscle lim protein upon axonal injury
por: Levin, Evgeny, et al.
Publicado: (2017)

Yokukansan Inhibits the Development of Morphine Tolerance by Regulating Presynaptic Proteins in DRG Neurons
por: Ohashi, Yusuke, et al.
Publicado: (2022)

Activation of neurons and satellite glial cells in the DRG produces morphine-induced hyperalgesia
por: Yamakita, Shunsuke, et al.
Publicado: (2023)

Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury
por: Wang, Yiqun, et al.
Publicado: (2023)

Upregulation of T-type Ca(2+) channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons
por: Duzhyy, Dmytro E, et al.
Publicado: (2015)

KLHL21, a novel gene that contributes to the progression of hepatocellular carcinoma
por: Shi, Lei, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_u4u6d8n0cb3qatvf2a1dn0sk8t