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Neuronal nitric oxide synthase regulation of calcium cycling in ventricular cardiomyocytes is independent of Ca(v)1.2 channel modulation under basal conditions

Neuronal nitric oxide synthase (nNOS) is considered a regulator of Ca(v)1.2 L-type Ca(2+) channels and downstream Ca(2+) cycling in the heart. The commonest view is that nitric oxide (NO), generated by nNOS activity in cardiomyocytes, reduces the currents through Ca(v)1.2 channels. This gives rise t...

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Detalles Bibliográficos
Autores principales:	Ebner, Janine, Cagalinec, Michal, Kubista, Helmut, Todt, Hannes, Szabo, Petra L., Kiss, Attila, Podesser, Bruno K., Cserne Szappanos, Henrietta, Hool, Livia C., Hilber, Karlheinz, Koenig, Xaver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2019
Materias:	Ion Channels, Receptors and Transporters
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960210/ https://www.ncbi.nlm.nih.gov/pubmed/31822999 http://dx.doi.org/10.1007/s00424-019-02335-7

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