RBP2 stabilizes slow Cav1.3 Ca(2+) channel inactivation properties of cochlear inner hair cells

Cav1.3 L-type Ca(2+) channels (LTCCs) in cochlear inner hair cells (IHCs) are essential for hearing as they convert sound-induced graded receptor potentials into tonic postsynaptic glutamate release. To enable fast and indefatigable presynaptic Ca(2+) signaling, IHC Cav1.3 channels exhibit a negativ...

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Detalles Bibliográficos
Autores principales: Ortner, Nadine J., Pinggera, Alexandra, Hofer, Nadja T., Siller, Anita, Brandt, Niels, Raffeiner, Andrea, Vilusic, Kristina, Lang, Isabelle, Blum, Kerstin, Obermair, Gerald J., Stefan, Eduard, Engel, Jutta, Striessnig, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Ion Channels, Receptors and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960213/
https://www.ncbi.nlm.nih.gov/pubmed/31848688
http://dx.doi.org/10.1007/s00424-019-02338-4

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