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Wearable Electronics Assess the Effectiveness of Transcranial Direct Current Stimulation on Balance and Gait in Parkinson’s Disease Patients

Currently, clinical evaluation represents the primary outcome measure in Parkinson’s disease (PD). However, clinical evaluation may underscore some subtle motor impairments, hidden from the visual inspection of examiners. Technology-based objective measures are more frequently utilized to assess mot...

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Autores principales: Ricci, Mariachiara, Di Lazzaro, Giulia, Pisani, Antonio, Scalise, Simona, Alwardat, Mohammad, Salimei, Chiara, Giannini, Franco, Saggio, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960759/
https://www.ncbi.nlm.nih.gov/pubmed/31835822
http://dx.doi.org/10.3390/s19245465
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author Ricci, Mariachiara
Di Lazzaro, Giulia
Pisani, Antonio
Scalise, Simona
Alwardat, Mohammad
Salimei, Chiara
Giannini, Franco
Saggio, Giovanni
author_facet Ricci, Mariachiara
Di Lazzaro, Giulia
Pisani, Antonio
Scalise, Simona
Alwardat, Mohammad
Salimei, Chiara
Giannini, Franco
Saggio, Giovanni
author_sort Ricci, Mariachiara
collection PubMed
description Currently, clinical evaluation represents the primary outcome measure in Parkinson’s disease (PD). However, clinical evaluation may underscore some subtle motor impairments, hidden from the visual inspection of examiners. Technology-based objective measures are more frequently utilized to assess motor performance and objectively measure motor dysfunction. Gait and balance impairments, frequent complications in later disease stages, are poorly responsive to classic dopamine-replacement therapy. Although recent findings suggest that transcranial direct current stimulation (tDCS) can have a role in improving motor skills, there is scarce evidence for this, especially considering the difficulty to objectively assess motor function. Therefore, we used wearable electronics to measure motor abilities, and further evaluated the gait and balance features of 10 PD patients, before and (three days and one month) after the tDCS. To assess patients’ abilities, we adopted six motor tasks, obtaining 72 meaningful motor features. According to the obtained results, wearable electronics demonstrated to be a valuable tool to measure the treatment response. Meanwhile the improvements from tDCS on gait and balance abilities of PD patients demonstrated to be generally partial and selective.
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spelling pubmed-69607592020-01-23 Wearable Electronics Assess the Effectiveness of Transcranial Direct Current Stimulation on Balance and Gait in Parkinson’s Disease Patients Ricci, Mariachiara Di Lazzaro, Giulia Pisani, Antonio Scalise, Simona Alwardat, Mohammad Salimei, Chiara Giannini, Franco Saggio, Giovanni Sensors (Basel) Article Currently, clinical evaluation represents the primary outcome measure in Parkinson’s disease (PD). However, clinical evaluation may underscore some subtle motor impairments, hidden from the visual inspection of examiners. Technology-based objective measures are more frequently utilized to assess motor performance and objectively measure motor dysfunction. Gait and balance impairments, frequent complications in later disease stages, are poorly responsive to classic dopamine-replacement therapy. Although recent findings suggest that transcranial direct current stimulation (tDCS) can have a role in improving motor skills, there is scarce evidence for this, especially considering the difficulty to objectively assess motor function. Therefore, we used wearable electronics to measure motor abilities, and further evaluated the gait and balance features of 10 PD patients, before and (three days and one month) after the tDCS. To assess patients’ abilities, we adopted six motor tasks, obtaining 72 meaningful motor features. According to the obtained results, wearable electronics demonstrated to be a valuable tool to measure the treatment response. Meanwhile the improvements from tDCS on gait and balance abilities of PD patients demonstrated to be generally partial and selective. MDPI 2019-12-11 /pmc/articles/PMC6960759/ /pubmed/31835822 http://dx.doi.org/10.3390/s19245465 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ricci, Mariachiara
Di Lazzaro, Giulia
Pisani, Antonio
Scalise, Simona
Alwardat, Mohammad
Salimei, Chiara
Giannini, Franco
Saggio, Giovanni
Wearable Electronics Assess the Effectiveness of Transcranial Direct Current Stimulation on Balance and Gait in Parkinson’s Disease Patients
title Wearable Electronics Assess the Effectiveness of Transcranial Direct Current Stimulation on Balance and Gait in Parkinson’s Disease Patients
title_full Wearable Electronics Assess the Effectiveness of Transcranial Direct Current Stimulation on Balance and Gait in Parkinson’s Disease Patients
title_fullStr Wearable Electronics Assess the Effectiveness of Transcranial Direct Current Stimulation on Balance and Gait in Parkinson’s Disease Patients
title_full_unstemmed Wearable Electronics Assess the Effectiveness of Transcranial Direct Current Stimulation on Balance and Gait in Parkinson’s Disease Patients
title_short Wearable Electronics Assess the Effectiveness of Transcranial Direct Current Stimulation on Balance and Gait in Parkinson’s Disease Patients
title_sort wearable electronics assess the effectiveness of transcranial direct current stimulation on balance and gait in parkinson’s disease patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960759/
https://www.ncbi.nlm.nih.gov/pubmed/31835822
http://dx.doi.org/10.3390/s19245465
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