Inhibition of protein FAK enhances 5-FU chemosensitivity to gastric carcinoma via p53 signaling pathways

The small molecule drug 5-fluorouracil (5-FU) is widely used in the treatment for gastric cancer (GC), however, it exerts poor efficacy and is associated with acquired and intrinsic resistance. Focal adhesion kinase (FAK), a non-receptor tyrosine kinase, plays a key role in adhesion, migration, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Jingjing, Tan, Yuyu, Su, Chen, Wang, Tao, Gao, Zhixing, Song, Dan, Zhao, Jiabao, Liao, Yueting, Liu, Xiaotian, Jiang, Ying, Feng, Qian, Wan, Zhong, Yu, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961071/
https://www.ncbi.nlm.nih.gov/pubmed/31969973
http://dx.doi.org/10.1016/j.csbj.2019.12.010

Ejemplares similares

Ejemplares similares