The effect of ageing on the resolution of inflammation

Ageing is associated with the development of a low-level, systemic, chronic inflammation known as “inflammaging”. This chronic inflammatory state can contribute to diseases of ageing such as sarcopenia and frailty. The presence of inflammaging suggests a failure of the cell clearance mechanisms that...

Descripción completa

Detalles Bibliográficos
Autor principal: Sendama, Wezi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961112/
https://www.ncbi.nlm.nih.gov/pubmed/31862417
http://dx.doi.org/10.1016/j.arr.2019.101000
_version_ 1783487925702361088
author Sendama, Wezi
author_facet Sendama, Wezi
author_sort Sendama, Wezi
collection PubMed
description Ageing is associated with the development of a low-level, systemic, chronic inflammation known as “inflammaging”. This chronic inflammatory state can contribute to diseases of ageing such as sarcopenia and frailty. The presence of inflammaging suggests a failure of the cell clearance mechanisms that ordinarily aid in the resolution of inflammation after pathogen infiltration or tissue injury. This review aims to explore what is known of how the processes involved in the resolution of inflammation might become defective with age.
format Online
Article
Text
id pubmed-6961112
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier Science
record_format MEDLINE/PubMed
spelling pubmed-69611122020-01-22 The effect of ageing on the resolution of inflammation Sendama, Wezi Ageing Res Rev Article Ageing is associated with the development of a low-level, systemic, chronic inflammation known as “inflammaging”. This chronic inflammatory state can contribute to diseases of ageing such as sarcopenia and frailty. The presence of inflammaging suggests a failure of the cell clearance mechanisms that ordinarily aid in the resolution of inflammation after pathogen infiltration or tissue injury. This review aims to explore what is known of how the processes involved in the resolution of inflammation might become defective with age. Elsevier Science 2020-01 /pmc/articles/PMC6961112/ /pubmed/31862417 http://dx.doi.org/10.1016/j.arr.2019.101000 Text en © 2019 The Author http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sendama, Wezi
The effect of ageing on the resolution of inflammation
title The effect of ageing on the resolution of inflammation
title_full The effect of ageing on the resolution of inflammation
title_fullStr The effect of ageing on the resolution of inflammation
title_full_unstemmed The effect of ageing on the resolution of inflammation
title_short The effect of ageing on the resolution of inflammation
title_sort effect of ageing on the resolution of inflammation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961112/
https://www.ncbi.nlm.nih.gov/pubmed/31862417
http://dx.doi.org/10.1016/j.arr.2019.101000
work_keys_str_mv AT sendamawezi theeffectofageingontheresolutionofinflammation
AT sendamawezi effectofageingontheresolutionofinflammation

Ejemplares similares