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Automatic construction of metabolic models with enzyme constraints
BACKGROUND: In order to improve the accuracy of constraint-based metabolic models, several approaches have been developed which intend to integrate additional biological information. Two of these methods, MOMENT and GECKO, incorporate enzymatic (kcat) parameters and enzyme mass constraints to furthe...
Autores principales: | Bekiaris, Pavlos Stephanos, Klamt, Steffen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961255/ https://www.ncbi.nlm.nih.gov/pubmed/31937255 http://dx.doi.org/10.1186/s12859-019-3329-9 |
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