Diverse approaches to predicting drug-induced liver injury using gene-expression profiles

BACKGROUND: Drug-induced liver injury (DILI) is a serious concern during drug development and the treatment of human disease. The ability to accurately predict DILI risk could yield significant improvements in drug attrition rates during drug development, in drug withdrawal rates, and in treatment o...

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Detalles Bibliográficos
Autores principales: Sumsion, G. Rex, Bradshaw, Michael S., Beales, Jeremy T., Ford, Emi, Caryotakis, Griffin R. G., Garrett, Daniel J., LeBaron, Emily D., Nwosu, Ifeanyichukwu O., Piccolo, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961287/
https://www.ncbi.nlm.nih.gov/pubmed/31941542
http://dx.doi.org/10.1186/s13062-019-0257-6

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