Cargando…

HIFI: estimating DNA-DNA interaction frequency from Hi-C data at restriction-fragment resolution

Hi-C is a popular technique to map three-dimensional chromosome conformation. In principle, Hi-C’s resolution is only limited by the size of restriction fragments. However, insufficient sequencing depth forces researchers to artificially reduce the resolution of Hi-C matrices at a loss of biological...

Descripción completa

Detalles Bibliográficos
Autores principales: Cameron, Christopher JF, Dostie, Josée, Blanchette, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961295/
https://www.ncbi.nlm.nih.gov/pubmed/31937349
http://dx.doi.org/10.1186/s13059-019-1913-y