Cargando…

Activity of enisamium, an isonicotinic acid derivative, against influenza viruses in differentiated normal human bronchial epithelial cells

AIMS: New therapeutics for the control of influenza virus infections are needed to alleviate the burden caused by seasonal epidemics and occasional pandemics, and to overcome the potential risk of drug-resistance emergence. Enisamium iodide (Amizon®, Farmak) is currently approved for clinical use fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boltz, David, Peng, Xinjian, Muzzio, Miguel, Dash, Pradyot, Thomas, Paul G, Margitich, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961345/ https://www.ncbi.nlm.nih.gov/pubmed/30466301 http://dx.doi.org/10.1177/2040206618811416

Ejemplares similares

Enisamium Inhibits SARS-CoV-2 RNA Synthesis
por: Elli, Stefano, et al.
Publicado: (2021)

Enisamium Reduces Influenza Virus Shedding and Improves Patient Recovery by Inhibiting Viral RNA Polymerase Activity
por: te Velthuis, Aartjan J. W., et al.
Publicado: (2021)

In Vitro Bioavailability Study of an Antiviral Compound Enisamium Iodide
por: Haltner-Ukomadu, Eleonore, et al.
Publicado: (2018)

Enisamium is an inhibitor of the SARS-CoV-2 RNA polymerase and shows improvement of recovery in COVID-19 patients in an interim analysis of a clinical trial
por: Holubovska, Olha, et al.
Publicado: (2021)

Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases
por: Walker, Alexander P, et al.
Publicado: (2020)

Flunarizinium isonicotinate
por: Kavitha, Channappa N., et al.
Publicado: (2014)

Isonicotinic Acid Hydrazide
Publicado: (1952)

Methyl isonicotinate 1-oxide
por: Li, Hui, et al.
Publicado: (2010)

Isonicotinic Acid Hydrazide in the Treatment of Lupus Vulgaris
por: Bhattacharyya, M., et al.
Publicado: (1954)

Molecular chains of coordinated dimolybdenum isonicotinate paddlewheel clusters
por: Li, Minyuan M., et al.
Publicado: (2019)

Specific alterations in riboproteomes composition of isonicotinic acid treated arabidopsis seedlings
por: Fakih, Zainab, et al.
Publicado: (2023)

The Effect of Hydrazine Derivatives of Isonicotinic Acid on the Infection of Mice with M. Tuberculosis Var. Bovis
por: Grunberg, E., et al.
Publicado: (1952)

Synthesis and Characterization of Novel Hydrazone Derivatives of Isonicotinic Hydrazide and Their Evaluation for Antibacterial and Cytotoxic Potential
por: Shah, Muhammad Abdullah, et al.
Publicado: (2022)

A Simple Method for Synthesis of Active Esters of Isonicotinic and Picolinic Acids
por: Christensen, Jørn B.
Publicado: (2001)

Distribution of Rhodium in Mice Submitted to Treatment With the Adduct of Rhodium Propionate and Sodium Isonicotinate
por: de Souza, Aparecido Ribeiro, et al.
Publicado: (1997)

Respiratory Syncytial Virus Inhibits Ciliagenesis in Differentiated Normal Human Bronchial Epithelial Cells: Effectiveness of N-Acetylcysteine
por: Mata, Manuel, et al.
Publicado: (2012)

THE LATHYROGENIC EFFECT OF ISONICOTINIC ACID HYDRAZIDE (INAH) ON THE CHICK EMBRYO AND ITS REVERSAL BY PYRIDOXAL
por: Levene, C. I.
Publicado: (1961)

Nocardia globerula NHB-2 nitrilase catalysed biotransformation of 4-cyanopyridine to isonicotinic acid
por: Sharma, Nitya Nand, et al.
Publicado: (2012)

Crystal structure of dichloridobis(methyl isonicotinate-κN)copper(II)
por: Ahadi, Elaheh, et al.
Publicado: (2015)

Tuberculosis of the Skin—Assessment of Clinical and Histological Changes Following Isonicotinic Acid Hydrazide Therapy
por: Gass, Robert H., et al.
Publicado: (1954)

Intravaginal isonicotinic acid hydrazide (INH) versus misoprostol for cervical ripening prior to hysteroscopy
por: Haghighi, Ladan, et al.
Publicado: (2020)

Synthesis of Highly Potent Anti-Inflammatory Compounds (ROS Inhibitors) from Isonicotinic Acid
por: Yaqoob, Sana, et al.
Publicado: (2021)

The Treatment of Pulmonary Tuberculosis, T. B. Meningitis and T. B. Pericarditis with the Combination of Isonicotinic Acid Hydrazide and Streptomycin
por: Patel, Bhaskar, et al.
Publicado: (1954)

The Formation of a Unique 2D Isonicotinate Polymer Driven by Cu(II) Aerobic Oxidation
por: Sánchez-Férez, Francisco, et al.
Publicado: (2023)

The Effect of Bergenin on Isonicotinic Acid Hydrazide and Rifampicin-Induced Liver Injury Revealed by RNA Sequencing
por: Li, Ting, et al.
Publicado: (2023)

Mechanical compression attenuates normal human bronchial epithelial wound healing
por: Arold, Stephen P, et al.
Publicado: (2009)

Xenobiotic metabolism in differentiated human bronchial epithelial cells
por: Boei, Jan J. W. A., et al.
Publicado: (2016)

Control of growth and squamous differentiation in normal human bronchial epithelial cells by chemical and biological modifiers and transferred genes.
por: Pfeifer, A M, et al.
Publicado: (1989)

Differential innate immune responses of human macrophages and bronchial epithelial cells against Talaromyces marneffei
por: Tan, Yen-Pei, et al.
Publicado: (2023)

Impaired Differentiation of Chronic Obstructive Pulmonary Disease Bronchial Epithelial Cells Grown on Bronchial Scaffolds
por: Hedström, Ulf, et al.
Publicado: (2021)

2-(1H-Benzotriazol-1-yl)-1-(3-methoxybenzoyl)ethyl isonicotinate
por: Wang, Wei, et al.
Publicado: (2009)

Metal-free thermal organocatalytic pinacol coupling of arylaldehydes using an isonicotinate catalyst with bis(pinacolato)diboron
por: Yasui, Masamichi, et al.
Publicado: (2021)

Formation of Ciprofloxacin–Isonicotinic Acid Cocrystal Using Mechanochemical Synthesis Routes—An Investigation into Critical Process Parameters
por: Karimi-Jafari, Maryam, et al.
Publicado: (2022)

Impact of Isonicotinic Acid Blending in Chitosan/Polyvinyl Alcohol on Ripening-Dependent Changes of Green Stage Tomato
por: Taher, Mohamed A., et al.
Publicado: (2023)

E-Cigarette Affects the Metabolome of Primary Normal Human Bronchial Epithelial Cells
por: Aug, Argo, et al.
Publicado: (2015)

Comparative Study of the Treatment of Tuberculous Cervical Lymphadenitis with Special Reference of Streptomycin, P.A.S. and Isonicotinic Acid Hydrazide
por: Almast, Sansar Chand
Publicado: (1953)

CHAC1 Is Differentially Expressed in Normal and Cystic Fibrosis Bronchial Epithelial Cells and Regulates the Inflammatory Response Induced by Pseudomonas aeruginosa
por: Perra, Léa, et al.
Publicado: (2018)

Diesel exhaust particles induce autophagy and citrullination in Normal Human Bronchial Epithelial cells
por: Colasanti, Tania, et al.
Publicado: (2018)

Extended lifespan of bronchial epithelial cells maintains normal cellular phenotype and transcriptome integrity
por: O'Loughlin, Jonathan, et al.
Publicado: (2021)

Haemophilus influenzae causes cellular trans-differentiation in human bronchial epithelia
por: Glöckner, Michael, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_svmekq4aekffs54kpiuugc5gu9