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Tissue-specific transcriptomic changes associated with AmBisome® treatment of BALB/c mice with experimental visceral leishmaniasis
Background: Liposomal amphotericin B (AmBisome®) as a treatment modality for visceral leishmaniasis (VL) has had significant impact on patient care in some but not all regions where VL is endemic. As the mode of action of AmBisome® in vivo is poorly understood, we compared the tissue-specific trans...
Autores principales: | Forrester, Sarah, Siefert, Karin, Ashwin, Helen, Brown, Najmeeyah, Zelmar, Andrea, James, Sally, Lagos, Dimitris, Timmis, Jon, Chatterjee, Mitali, Mottram, Jeremy C., Croft, Simon L., Kaye, Paul M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961418/ https://www.ncbi.nlm.nih.gov/pubmed/31976381 http://dx.doi.org/10.12688/wellcomeopenres.15606.1 |
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