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Evolutionarily Conserved Pachytene piRNA Loci are Highly Divergent among Modern Humans

In the fetal mouse testis, PIWI Interacting RNAs (piRNAs) guide PIWI proteins to silence transposons, but after birth, most post-pubertal pachytene piRNAs map to the genome uniquely and are thought to regulate genes required for male fertility. In human males, the developmental classes, precise geno...

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Detalles Bibliográficos
Autores principales:	Özata, Deniz M, Yu, Tianxiong, Mou, Haiwei, Gainetdinov, Ildar, Colpan, Cansu, Cecchini, Katharine, Kaymaz, Yasin, Wu, Pei-Hsuan, Fan, Kaili, Kucukural, Alper, Weng, Zhiping, Zamore, Phillip D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961462/ https://www.ncbi.nlm.nih.gov/pubmed/31900453 http://dx.doi.org/10.1038/s41559-019-1065-1

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