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Multiple Environmental Signaling Pathways Control the Differentiation of RORγt-Expressing Regulatory T Cells
RORγt-expressing Tregs form a specialized subset of intestinal CD4(+) Foxp3(+) cells which is essential to maintain gut homeostasis and tolerance to commensal microbiota. Recently, c-Maf emerged as a critical factor in the regulation of RORγt expression in Tregs. However, aside from c-Maf signaling,...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961548/ https://www.ncbi.nlm.nih.gov/pubmed/31998303 http://dx.doi.org/10.3389/fimmu.2019.03007 |