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Quality Control Strategy for CRISPR-Cas9-Based Gene Editing Complicated by a Pseudogene

CRISPR-Cas9 mediated gene editing in induced pluripotent stem cells became an efficient tool to investigate biological mechanisms underlying genetic-driven diseases while accounting for the respective genetic background. This technique relies on the targeting of a specific nucleotide sequence presen...

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Detalles Bibliográficos
Autores principales:	Hanss, Zoé, Boussaad, Ibrahim, Jarazo, Javier, Schwamborn, Jens C., Krüger, Rejko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961559/ https://www.ncbi.nlm.nih.gov/pubmed/31998363 http://dx.doi.org/10.3389/fgene.2019.01297

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