Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9

Targeting definite genomic locations using CRISPR-Cas systems requires a set of enzymes with unique protospacer adjacent motif (PAM) compatibilities. To expand this repertoire, we engineered nucleases, cytosine base editors, and adenine base editors from the archetypal Streptococcus thermophilus CRI...

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Detalles Bibliográficos
Autores principales: Agudelo, Daniel, Carter, Sophie, Velimirovic, Minja, Duringer, Alexis, Rivest, Jean-François, Levesque, Sébastien, Loehr, Jeremy, Mouchiroud, Mathilde, Cyr, Denis, Waters, Paula J., Laplante, Mathieu, Moineau, Sylvain, Goulet, Adeline, Doyon, Yannick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961573/
https://www.ncbi.nlm.nih.gov/pubmed/31900288
http://dx.doi.org/10.1101/gr.255414.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961573/
https://www.ncbi.nlm.nih.gov/pubmed/31900288
http://dx.doi.org/10.1101/gr.255414.119

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