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Predicting transfer RNA gene activity from sequence and genome context

Transfer RNA (tRNA) genes are among the most highly transcribed genes in the genome owing to their central role in protein synthesis. However, there is evidence for a broad range of gene expression across tRNA loci. This complexity, combined with difficulty in measuring transcript abundance and high...

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Detalles Bibliográficos
Autores principales: Thornlow, Bryan P., Armstrong, Joel, Holmes, Andrew D., Howard, Jonathan M., Corbett-Detig, Russell B., Lowe, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961574/
https://www.ncbi.nlm.nih.gov/pubmed/31857444
http://dx.doi.org/10.1101/gr.256164.119