Overexpression of CD6 and PD-1 Identifies Dysfunctional CD8(+) T-Cells During Chronic SIV Infection of Rhesus Macaques

Effective CD8(+) T-cell responses play an important role in determining the course of SIV/HIV viral infection. Here we identified a unique population of dysfunctional CD8(+) T-cells in lymphoid tissues and bronchoalveolar lavage (BAL) of rhesus macaques with chronic SIV infection characterized by co...

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Detalles Bibliográficos
Autores principales: Enyindah-Asonye, Gospel, Nwankwo, Anthony, Rahman, Mohammad Arif, Hunegnaw, Ruth, Hogge, Christopher, Helmold Hait, Sabrina, Ko, Eun-Ju, Hoang, Tanya, Robert-Guroff, Marjorie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961594/
https://www.ncbi.nlm.nih.gov/pubmed/31998302
http://dx.doi.org/10.3389/fimmu.2019.03005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961594/
https://www.ncbi.nlm.nih.gov/pubmed/31998302
http://dx.doi.org/10.3389/fimmu.2019.03005

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