Tumor-Derived Soluble MICA Obstructs the NKG2D Pathway to Restrain NK Cytotoxicity

The natural killer group 2D (NKG2D) receptor and its ligands play important roles in immune surveillance. In this study, we observed that the average serum soluble MICA (sMICA) concentration of 174 hepatocellular carcinoma (HCC) patients was significantly higher than that in 80 healthy subjects (602...

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Detalles Bibliográficos
Autores principales: Luo, Qizhi, Luo, Weiguang, Zhu, Quan, Huang, Hongjun, Peng, Huiyun, Liu, Rongjiao, Xie, Min, Li, Shili, Li, Ming, Hu, Xiaocui, Zou, Yizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2020
Materias:
Orginal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961768/
https://www.ncbi.nlm.nih.gov/pubmed/32010486
http://dx.doi.org/10.14336/AD.2019.1017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961768/
https://www.ncbi.nlm.nih.gov/pubmed/32010486
http://dx.doi.org/10.14336/AD.2019.1017

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