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Tumor-Derived Soluble MICA Obstructs the NKG2D Pathway to Restrain NK Cytotoxicity
The natural killer group 2D (NKG2D) receptor and its ligands play important roles in immune surveillance. In this study, we observed that the average serum soluble MICA (sMICA) concentration of 174 hepatocellular carcinoma (HCC) patients was significantly higher than that in 80 healthy subjects (602...
Autores principales: | Luo, Qizhi, Luo, Weiguang, Zhu, Quan, Huang, Hongjun, Peng, Huiyun, Liu, Rongjiao, Xie, Min, Li, Shili, Li, Ming, Hu, Xiaocui, Zou, Yizhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961768/ https://www.ncbi.nlm.nih.gov/pubmed/32010486 http://dx.doi.org/10.14336/AD.2019.1017 |
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