Long-term HIV-1 Tat Expression in the Brain Led to Neurobehavioral, Pathological, and Epigenetic Changes Reminiscent of Accelerated Aging

HIV infects the central nervous system and causes HIV/neuroAIDS, which is predominantly manifested in the form of mild cognitive and motor disorder in the era of combination antiretroviral therapy. HIV Tat protein is known to be a major pathogenic factor for HIV/neuroAIDS through a myriad of direct...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaojie, Fan, Yan, Vann, Philip H., Wong, Jessica M., Sumien, Nathalie, He, Johnny J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2020
Materias:
Orginal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961778/
https://www.ncbi.nlm.nih.gov/pubmed/32010484
http://dx.doi.org/10.14336/AD.2019.0323

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