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Ultrastructure of light-activated axons following optogenetic stimulation to produce late-phase long-term potentiation
Analysis of neuronal compartments has revealed many state-dependent changes in geometry but establishing synapse-specific mechanisms at the nanoscale has proven elusive. We co-expressed channelrhodopsin2-GFP and mAPEX2 in a subset of hippocampal CA3 neurons and used trains of light to induce late-ph...
Autores principales: | Kuwajima, Masaaki, Ostrovskaya, Olga I., Cao, Guan, Weisberg, Seth A., Harris, Kristen M., Zemelman, Boris V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961864/ https://www.ncbi.nlm.nih.gov/pubmed/31940316 http://dx.doi.org/10.1371/journal.pone.0226797 |
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