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Evaluation of KRAS, NRAS and BRAF mutations detection in plasma using an automated system for patients with metastatic colorectal cancer

BACKGROUND: Cell-free DNA detection is becoming a surrogate assay for tumor genotyping. Biological fluids often content a very low amount of cell-free tumor DNA and assays able to detect very low allele frequency mutant with a few quantities of DNA are required. We evaluated the ability of the fully...

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Detalles Bibliográficos
Autores principales:	Franczak, Claire, Witz, Andréa, Geoffroy, Karen, Demange, Jessica, Rouyer, Marie, Husson, Marie, Massard, Vincent, Gavoille, Céline, Lambert, Aurélien, Gilson, Pauline, Gambier, Nicolas, Scala-Bertola, Julien, Merlin, Jean-Louis, Harlé, Alexandre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961936/ https://www.ncbi.nlm.nih.gov/pubmed/31940389 http://dx.doi.org/10.1371/journal.pone.0227294

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