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Uncoupled turnover disrupts mitochondrial quality control in diabetic retinopathy

Mitochondrial quality control (MQC) is crucial for regulating CNS homeostasis, and its disruption has been implicated in the pathogenesis of some of the most common neurodegenerative diseases. In healthy tissues, the maintenance of MQC depends upon an exquisite balance between mitophagy (removal of...

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Detalles Bibliográficos
Autores principales:	Hombrebueno, Jose R., Cairns, Lauren, Dutton, Louise R., Lyons, Timothy J., Brazil, Derek P., Moynagh, Paul, Curtis, Tim M., Xu, Heping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962019/ https://www.ncbi.nlm.nih.gov/pubmed/31661466 http://dx.doi.org/10.1172/jci.insight.129760

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