KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern

BACKGROUND: The presence of an early repolarization pattern (ERP) on the surface ECG is associated with risk of ventricular fibrillation and sudden cardiac death. Family studies have shown that ERP is a highly heritable trait, but molecular genetic determinants are unknown. METHODS: To identify gene...

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Detalles Bibliográficos
Autores principales: Teumer, Alexander, Trenkwalder, Teresa, Kessler, Thorsten, Jamshidi, Yalda, van den Berg, Marten E., Kaess, Bernhard, Nelson, Christopher P., Bastiaenen, Rachel, De Bortoli, Marzia, Rossini, Alessandra, Deisenhofer, Isabel, Stark, Klaus, Assa, Solmaz, Braund, Peter S., Cabrera, Claudia, Dominiczak, Anna F., Gögele, Martin, Hall, Leanne M., Ikram, M. Arfan, Kavousi, Maryam, Lackner, Karl J., Müller, Christian, Münzel, Thomas, Nauck, Matthias, Padmanabhan, Sandosh, Pfeiffer, Norbert, Spector, Tim D., Uitterlinden, Andre G., Verweij, Niek, Völker, Uwe, Warren, Helen R., Zafar, Mobeen, Felix, Stephan B., Kors, Jan A., Snieder, Harold, Munroe, Patricia B., Pattaro, Cristian, Fuchsberger, Christian, Schmidt, Georg, Nolte, Ilja M., Schunkert, Heribert, Pramstaller, Peter P., Wild, Philipp S., van der Harst, Pim, Stricker, Bruno H., Schnabel, Renate B., Samani, Nilesh J., Hengstenberg, Christian, Dörr, Marcus, Behr, Elijah R., Reinhard, Wibke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2019
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962032/
https://www.ncbi.nlm.nih.gov/pubmed/31600170
http://dx.doi.org/10.1172/jci.insight.131156

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