Acidic Microenvironment Regulates the Severity of Hepatic Ischemia/Reperfusion Injury by Modulating the Generation and Function of Tregs via the PI3K-mTOR Pathway

Hepatic ischemia/reperfusion injury (HIRI) is a major cause of liver dysfunction and even liver failure after liver transplantation and hepatectomy. One of the critical mechanisms that lead to HIRI is an acidic microenvironment, which develops due to the accumulation of high acid-like substances suc...

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Detalles Bibliográficos
Autores principales: Gan, Xiaojie, Zhang, Rongsheng, Gu, Jian, Ju, Zheng, Wu, Xiao, Wang, Qi, Peng, Hao, Qiu, Jiannan, Zhou, Jinren, Cheng, Feng, Lu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962105/
https://www.ncbi.nlm.nih.gov/pubmed/31998287
http://dx.doi.org/10.3389/fimmu.2019.02945

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