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Escalated Oxycodone Self-Administration and Punishment: Differential Expression of Opioid Receptors and Immediate Early Genes in the Rat Dorsal Striatum and Prefrontal Cortex

Opioid use disorder (OUD) is characterized by compulsive drug taking despite adverse life consequences. Here, we sought to identify neurobiological consequences associated with the behavioral effects of contingent footshocks administered after escalation of oxycodone self-administration. To reach th...

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Detalles Bibliográficos
Autores principales: Blackwood, Christopher A., McCoy, Michael T., Ladenheim, Bruce, Cadet, Jean Lud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962106/
https://www.ncbi.nlm.nih.gov/pubmed/31998063
http://dx.doi.org/10.3389/fnins.2019.01392