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Escalated Oxycodone Self-Administration and Punishment: Differential Expression of Opioid Receptors and Immediate Early Genes in the Rat Dorsal Striatum and Prefrontal Cortex
Opioid use disorder (OUD) is characterized by compulsive drug taking despite adverse life consequences. Here, we sought to identify neurobiological consequences associated with the behavioral effects of contingent footshocks administered after escalation of oxycodone self-administration. To reach th...
Autores principales: | Blackwood, Christopher A., McCoy, Michael T., Ladenheim, Bruce, Cadet, Jean Lud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962106/ https://www.ncbi.nlm.nih.gov/pubmed/31998063 http://dx.doi.org/10.3389/fnins.2019.01392 |
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