Two Vanilloid Ligand Bindings Per Channel Are Required to Transduce Capsaicin-Activating Stimuli

The tetrameric capsaicin receptor transient receptor potential vanilloid 1 (TRPV1) in mammals has evolved the capability to integrate pain signal arising from harmful temperature and chemical irritants. The four repetitions of TRPV1 subunits result in an ion channel with excellent pain sensitivity,...

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Detalles Bibliográficos
Autores principales: Liu, Ting-Yi, Chu, Ying, Mei, Hao-Ruei, Chang, Dennis, Chuang, Huai-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962233/
https://www.ncbi.nlm.nih.gov/pubmed/31998070
http://dx.doi.org/10.3389/fnmol.2019.00302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962233/
https://www.ncbi.nlm.nih.gov/pubmed/31998070
http://dx.doi.org/10.3389/fnmol.2019.00302

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