Recalling the Biological Significance of Immune Checkpoints on NK Cells: A Chance to Overcome LAG3, PD1, and CTLA4 Inhibitory Pathways by Adoptive NK Cell Transfer?

Immune checkpoint receptors (IC) positively or negatively regulate the activation of the host immune response, preventing unwanted reactions against self-healthy tissues. In recent years the term IC has been mainly used for the inhibitory ICs, which are critical to control Natural Killer (NK) and Cy...

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Detalles Bibliográficos
Autores principales: Lanuza, Pilar M., Pesini, Cecilia, Arias, Maykel A., Calvo, Carlota, Ramirez-Labrada, Ariel, Pardo, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962251/
https://www.ncbi.nlm.nih.gov/pubmed/31998304
http://dx.doi.org/10.3389/fimmu.2019.03010

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