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Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia

Asparagine Synthetase (ASNS) catalyzes the synthesis of the non-essential amino acid asparagine (Asn) from aspartate (Asp) and glutamine (Gln). ASNS expression is highly regulated at the transcriptional level, being induced by both the Amino Acid Response (AAR) and the Unfolded Protein Response (UPR...

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Detalles Bibliográficos
Autores principales:	Chiu, Martina, Taurino, Giuseppe, Bianchi, Massimiliano G., Kilberg, Michael S., Bussolati, Ovidio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962308/ https://www.ncbi.nlm.nih.gov/pubmed/31998641 http://dx.doi.org/10.3389/fonc.2019.01480

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